SCIN Antibody / Scinderin

NSJ Bioreagents
Product Code: NSJ-RQ7467
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ7467-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the Scinderin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) human T-47D, 2) rat kidney, 3) mouse kidney and 4) mouse small intestine tissue lysate with Scinderin antibody. Predictec molecular weight ~80 kDa.

Western blot testing of 1) human T-47D, 2) rat kidney, 3) mouse kidney and 4) mouse small intestine tissue lysate with Scinderin antibody. Predictec molecular weight ~80 kDa.

Documents

Further Information

Application Details:
Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Scinderin antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Scinderin (also known as Adseverin) is a protein that in humans is encoded by the SCIN gene. Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids S35-Y617) was used as the immunogen for the Scinderin antibody.
Limitation:
This Scinderin antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
Q9Y6U3