Surfactant protein D Antibody / SFTPD

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NSJ Bioreagents
Product Code: NSJ-V4098
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V4098-20UG20 ug£264.00
Quantity:
NSJ-V4098-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2b, lambda
Antibody Clonality: Monoclonal
Antibody Clone: SFTPD/4362
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the Pulmonary Surfactant-Associated Protein D antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Images

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Analysis of a HuProt(TM) microarray containing more than 19,000 full-length human proteins using Pulmonary Surfactant-Associated Protein D antibody (clone SFTPD/4362). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (in combination with a fluorescently-tagged anti-I
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Analysis of a HuProt(TM) microarray containing more than 19,000 full-length human proteins using Pulmonary Surfactant-Associated Protein D antibody (clone SFTPD/4362). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (in combination with a fluorescently-tagged anti-I

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
Description:
Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant partial protein (within amino acids 241-336) from the human protein was used as the immunogen for the Pulmonary Surfactant-Associated Protein D antibody.
Limitation:
This Pulmonary Surfactant-Associated Protein D antibody is available for research use only.
Localization:
Secreted
Purity:
Protein A/G affinity
Uniprot #:
P35247