SI-CLP Antibody / CHID1 / Chitinase Domain Containing 1
| Code | Size | Price |
|---|
| NSJ-V4152SAF-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: CHID1/6368
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the SI-CLP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
Description:
SI-CLP (stabilin-1 interacting chitinase-like), also known as CHID1 (chitinase domain-containing protein 1), is a 393 amino acid secreted protein that belongs to the glycosyl hydrolase 18 family. SI-CLP interacts with STAB1 and localizes to lysosome in cells of monocytic, T, B and epithelial origin. SI-CLP is a saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). The SI-CLP protein is up-regulated by IL4/interleukin-4 and dexamethasone in the macrophages, and is also up-regulated by glucocorticoid. Existing as three alternatively spliced isoforms, the SI-CLP gene is conserved in chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A. thaliana and rice, and maps to human chromosome 11p15.5.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant full-length human SI-CLP protein was used as the immunogen for the CHID1 antibody.
Limitation:
This SI-CLP antibody is available for research use only.
Localization:
Secreted, Cytoplasm
Purity:
Protein A/G affinity
Uniprot #:
Q9BWS9