SNW1 Antibody / NCoA-62 / SKIP
| Code | Size | Price |
|---|
| NSJ-V4353-20UG | 20 ug | £264.00 |
Quantity:
| NSJ-V4353-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: PCRP-SNW1-1C12
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
Storage:
Aliquot the SNW1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 2-4ug/ml
Description:
Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant fragment of human SNW1 protein was used as the immunogen for the SNW1 antibody.
Limitation:
This SNW1 antibody is available for research use only.
Localization:
Nucleus, cytoplasm
Purity:
Protein A/G affinity
Uniprot #:
Q13573