CD147 / Emmprin / Basigin Antibody

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NSJ Bioreagents
Product Code: NSJ-V4597SAF
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V4597SAF-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG
Antibody Clonality: Monoclonal
Antibody Clone: BSG/7952
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the Basigin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 3
Analysis of a HuProt(TM) microarray containing more than 19,000 full-length human proteins using Basigin antibody (clone BSG/7952). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a mAb to its intended target. A mAb is considered to specific to its intended target, if the mAb has an S-score of at least 2.5. For example, if a mAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that mAb to protein X is equal to 29.
2 / 3
Western blot testing of human THP-1 cell lysate with Basigin antibody (clone BSG/7952). Expected molecular weight: 27-66 kDa depending on level of glycosylation.
3 / 3
SDS-PAGE analysis of purified, BSA-free Basigin antibody (clone BSG/7952) as confirmation of integrity and purity.
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Analysis of a HuProt(TM) microarray containing more than 19,000 full-length human proteins using Basigin antibody (clone BSG/7952). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a mAb to its intended target. A mAb is considered to specific to its intended target, if the mAb has an S-score of at least 2.5. For example, if a mAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that mAb to protein X is equal to 29.
Western blot testing of human THP-1 cell lysate with Basigin antibody (clone BSG/7952). Expected molecular weight: 27-66 kDa depending on level of glycosylation.
SDS-PAGE analysis of purified, BSA-free Basigin antibody (clone BSG/7952) as confirmation of integrity and purity.

Documents

Further Information

Application Details:
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Description:
Basigin is expressed more intensely on thymocytes than on mature peripheral blood T cells. It is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant full-length human protein was used as the immunogen for the Basigin antibody.
Limitation:
This Basigin antibody is available for research use only.
Localization:
Cell surface
Purity:
Protein A/G affinity
Uniprot #:
P35613