SBSN Antibody / Suprabasin

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NSJ Bioreagents
Product Code: NSJ-V4624
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V4624-20UG20 ug£264.00
Quantity:
NSJ-V4624-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SBSN/7961
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the SBSN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC staining of FFPE human esophagus tissue with SBSN antibody (clone SBSN/7961). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~
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IHC staining of FFPE human esophagus tissue with SBSN antibody (clone SBSN/7961). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Description:
Suprabasin (SBSN) is a 247 amino acid secreted protein that is upregulated in differentiating keratinocytes and is though to play a role in epidermal differentiation. Expressed in uterus, skin, thymus and esophagus, suprabasin is encoded by a gene that maps to human chromosome 19q13.12. Chromosome 19 consists of about 63 million bases with over 1,400 genes, making up over 2% of human genomic DNA. Chromosome 19 is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fca receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and Insulin-dependent diabetes have been linked to chromosome 19.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant fragment from the human protein was used as the immunogen for the SBSN antibody.
Limitation:
This SBSN antibody is available for research use only.
Localization:
Cytoplasm, Secreted
Purity:
Protein A/G affinity
Uniprot #:
Q6UWP8