S100A12 Antibody / CGRP

NSJ Bioreagents
Product Code: NSJ-V4741SAF
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V4741SAF-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG, kappa
Antibody Clonality: Monoclonal
Antibody Clone: S100A12/8952R
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the CGRP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC staining of FFPE human spleen tissue with CGRP antibody (clone S100A12/8952R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~
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IHC staining of FFPE human spleen tissue with CGRP antibody (clone S100A12/8952R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~

Documents

Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Description:
The family of EF-hand type Ca2+-binding proteins includes Calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 Alpha and beta, Calgranulins A (also designated MRP8), B (also designated MRP14) and C (S100A12, CGRP) and the parvalbumin family members, including parvalbumin Alpha and parvalbumin beta (also designated oncomodulin). Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 Alpha and beta are present in a variety of other tissues, and Calbindin is present in intestine and kidney. Parvalbumin Alpha is also found in fast-contracting/relaxing skeletal muscle fibers and parvalbumin beta is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Calgranulin is expressed in macrophages and epithelial cells.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A recombinant partial protein sequence (within amino acids 1-95) from the human protein was used as the immunogen for the CGRP antibody.
Limitation:
This CGRP antibody is available for research use only.
Localization:
Secreted
Purity:
Protein A/G affinity
Uniprot #:
P80511