Estrogen Receptor alpha Antibody
| Code | Size | Price |
|---|
| NSJ-V5187SAF-100UG | 100 ug | £534.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: AER311
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
Storage:
Aliquot the ER alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details:
Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 1-2ug/ml
Description:
This mAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this mAb is mapped between amino acids 495-595 of E/F domain. Estrogen Receptor is an important regulator of growth and differentiation in the mammary gland. Presence of Estrogen Receptor in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Estrogen Receptor purified from cow uterus was used as the immunogen for the ER alpha antibody. The epitope of this mAb is mapped between amino acids 495-595.
Limitation:
This ER alpha antibody is available for research use only.
Localization:
Nuclear
Purity:
Protein A/G affinity
Uniprot #:
P03372