BMS 195614

TargetMol
Product Code: TAR-T22192
Supplier: TargetMol
CodeSizePrice
TAR-T22192-1mg1mg£216.00
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TAR-T22192-5mg5mg£406.00
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Quantity:
TAR-T22192-10mg10mg£568.00
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Quantity:
TAR-T22192-25mg25mg£864.00
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Quantity:
TAR-T22192-50mg50mg£1,139.00
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Quantity:
TAR-T22192-100mg100mg£1,500.00
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Quantity:
TAR-T22192-500mg500mg£2,946.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
BMS 195614 is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.
CAS:
253310-42-8
Molecular Weight:
448.51
Pathway:
Metabolism
Purity:
0.977
SMILES:
CC1(CC=C(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C4=CC5=CC=CC=C5N=C4)C
Target:
Retinoid Receptor

References

Nikolas Gunkel, Thorsten Meyer and John Michael Graettinger; N/A. Method of Modulating the Degree of Adipose Tissue Deposited Intramuscularly. US patent 20140094512A1. 2014 Apr. 3. Fern E. Murdoch and Erwin Goldberg. Male contraception: Another holy grail. Bioorg. Med. Chem. Lett., 2014, 24:419-424. Flamini Marina Ines, Gauna Gisel Valeria, Sottile Mayra Lis, et al. Retinoic acid reduces migration of human breast cancer cells: role of retinoic acid receptor ?. J. Cell. Mol. Med., 2014, 18(6): 1113-1123. F. Christopher Zusi, Matthew V. Lorenzi and Valerie Vivat-Hannah. Selective retinoids and rexinoids in cancer therapy and chemoprevention. Drug Discovery Today, 2002, 7(23):1165-1174. Sanny S. W. Chung, Rebecca A. D. Cuellar, Xiangyuan Wang, et al. Pharmacological Activity of Retinoic Acid Receptor Alpha-Selective Antagonists in Vitro and in Vivo. ACS Med. Chem. Lett., 2013, 4: 446-450.