AD57

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TargetMol
Product Code: TAR-T22552L
Supplier: TargetMol
CodeSizePrice
TAR-T22552L-1mg1mg£108.00
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Quantity:
TAR-T22552L-5mg5mg£229.00
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Quantity:
TAR-T22552L-1mL1 mL * 10 mM (in DMSO)£252.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22552L-10mg10mg£369.00
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Quantity:
TAR-T22552L-25mg25mg£576.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22552L-50mg50mg£790.00
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Quantity:
TAR-T22552L-100mg100mg£1,050.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T22552L-500mg500mg£2,038.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 uM and 0.041 uM, respectively.
CAS:
1093380-42-7
Molecular Weight:
455.44
Pathway:
Angiogenesis|Tyrosine Kinase/Adaptors|Cytoskeletal Signaling
Purity:
0.9823
SMILES:
O=C(NC=1C=CC(=CC1)C2=NN(C=3N=CN=C(N)C23)C(C)C)NC4=CC=CC(=C4)C(F)(F)F
Target:
Bcr-Abl|Src

References

Dar AC, Lopez MS, Shokat KM. Small molecule recognition of c-Src via the Imatinib-binding conformation. Chem Biol. 2008 Oct 20;15(10):1015-22.