PD 124895
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
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Documents
Further Information
Bioactivity:
PD 124895 is an antitumor antibiotic isolated from the fermentation broth of Streptomyces sp.
CAS:
107140-30-7
Formula:
C32H46O7
Molecular Weight:
542.713
Purity:
0.98
SMILES:
CC(C\C=C\C(\C)=C\C(CO)C(=O)C(C)C(O)C(C)C\C(C)=C\C(O)=O)\C=C(\C)/C=C/C1OC(=O)C=CC1C |c:35|
References
Umezawa I, Komiyama K. [Studies on the new antibiotic kazusamycin and related substances]. Gan To Kagaku Ryoho. 1987 Mar;14(3 Pt 2):858-64. Japanese. PubMed PMID: 3105461.
Takamiya K, Yoshida E, Takahashi T, Okura A, Okanishi M, Komiyama K, Umezawa I. The effect of kazusamycin B on the cell cycle and morphology of cultured L1210 cells. J Antibiot (Tokyo). 1988 Dec;41(12):1854-61. PubMed PMID: 3209477.
Funaishi K, Kawamura K, Sugiura Y, Nakahori N, Yoshida E, Okanishi M, Umezawa I, Funayama S, Komiyama K. Kazusamycin B, a novel antitumor antibiotic. J Antibiot (Tokyo). 1987 Jun;40(6):778-85. PubMed PMID: 3610834.
Hurley TR, Bunge RH, Willmer NE, Hokanson GC, French JC. PD 124,895 and PD 124,966, two new antitumor antibiotics. J Antibiot (Tokyo). 1986 Dec;39(12):1651-6. PubMed PMID: 3818438.