β-Defensin-2 (human) (trifluoroacetate salt)
| Code | Size | Price |
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| TAR-T35451-1mg | 1mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of periodontopathogenic and cariogenic bacteria, includingP. gingivalisandS. salivarius.
Purity:
0.98
References
Niyonsaba, F., Ushio, H., Nakano, N., et al.Antimicrobial peptides human ?-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokinesJ. Invest. Dermatol.127(3)594-604(2007)
Ouhara, K., Komatsuzawa, H., Yamada, S., et al.Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, ?-defensins and LL37, produced by human epithelial cellsJ. Antimicrob. Chemother.55(6)888-896(2005)
Huh, W.-K., Oono, T., Shirafuji, Y., et al.Dynamic alteration of human ?-defensin 2 localization from cytoplasm to intercellular space in psoriatic skinJ. Mol. Med. (Berl.)80(10)678-684(2002)
Lehrer, R.I.Primate defensinsNat. Rev. Microbiol.2(9)727-738(2004)
Butmarc, J., Yufit, T., Carson, P., et al.Human ?-defensin-2 expression is increased in chronic woundsWound Repair Regen.12(4)439-443(2004)
Niyonsaba, F., Ushio, H., Hara, M., et al.Antimicrobial peptides human ?-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cellsJ. Immunol.184(7)3526-3534(2010)