(±)16-HETE
| Code | Size | Price |
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| TAR-T35465-1mg | 1mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (?)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, however 16(S)-HETE does not affect perfusion pressure. At a concentration of 2 uM the (S)-enantiomer of 16-HETE inhibits proximal tubule ATPase activity by as much as 60%, whereas the (R)-isomer has negligible effects on ATPase activity.
CAS:
128914-46-5
Formula:
C20H32O3
Molecular Weight:
320.473
Purity:
0.98
SMILES:
CCCCC(O)\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O