(±)13(14)-EpDPA
| Code | Size | Price |
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| TAR-T35496-1mg | 1mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (?)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 uM. (?)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (?)13(14)-EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.
CAS:
895127-64-7
Formula:
C22H32O3
Molecular Weight:
344.495
Purity:
0.98
SMILES:
CC\C=C/C\C=C/CC1OC1C\C=C/C\C=C/C\C=C/CCC(O)=O