12-HETE
Code | Size | Price |
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TAR-T35507-1mg | 1mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
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Further Information
Bioactivity:
(?)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (?)12-HETE is similar to that of its constituent enantiomers . It aggregates neutrophils with an EC50 value of 40 nM.[1]
CAS:
71030-37-0
Formula:
C20H32O3
Molecular Weight:
320.473
Purity:
0.98
SMILES:
CCCCC\C=C/CC(O)\C=C\C=C/C\C=C/CCCC(O)=O
References
O'Flaherty, J.T., Thomas, M.J., Lees, C.J., et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. American Journal of Pathology 104, 55-62 (1981).