Ochratoxin A-13C20
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Ochratoxin A-13C20is intended for use as an internal standard for the quantification of ochratoxin A by GC- or LC-MS. Ochratoxin A is a mycotoxin that has been found inAspergillusandPenicillium.1It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 ug/kg.2Topical application of ochratoxin A (80 ug/mouse) induces DNA damage, cell cycle arrest at the G0/G1phase, and apoptosis in mouse skin cells.1It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A has been found as a contaminant in a variety of foods.3
CAS:
911392-42-2
Molecular Weight:
423.66
Purity:
0.98
SMILES:
[13CH3][13C@@H]1[13CH2][13c]2[13c](Cl)[13cH][13c]([13C](=O)N[13C@@H]([13CH2][13c]3[13cH][13cH][13cH][13cH][13cH]3)[13C](O)=O)[13c](O)[13c]2[13C](=O)O1
References
Petrik, J., Zani?-Grubisi?, T., Barisi?, K., et al.Apoptosis and oxidative stress induced by ochratoxin A in rat kidneyArch. Toxicol.77(12)685-693(2003)
Kumar, R., Ansari, K.M., Chaudhari, B.P., et al.Topical application of ochratoxin A causes DNA damage and tumor initiation in mouse skinPLoS One7(10)(2012)
Program, N.T.Ochratoxin A: CAS No. 303-47-9Report on Carcinogens12335-337(2011)