16(R)-HETE

TargetMol
Product Code: TAR-T35847
Supplier: TargetMol
CodeSizePrice
TAR-T35847-1mg1mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

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Further Information

Bioactivity:
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase activity by as much as 60% at a concentration of 2 µM.[1]
CAS:
183509-22-0
Formula:
C20H32O3
Molecular Weight:
320.473
Purity:
0.98
SMILES:
CCCC[C@@H](O)\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O

References

Carroll, M.A., Balazy, M., Margiotta, P., et al. Cytochrome P-450-d]ependent HETEs: Profile of biological activity and stimulation by vasoactive peptides. American Journal of Physiology 271, R863-R869 (1996).