N,N-Didesethyl Sunitinib Hydrochloride

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TargetMol
Product Code: TAR-T60128
Supplier: TargetMol
CodeSizePrice
TAR-T60128-1mg1mg£227.00
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TAR-T60128-2mg2mg£306.00
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TAR-T60128-5mg5mg£430.00
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TAR-T60128-1mL1 mL * 10 mM (in DMSO)£454.00
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TAR-T60128-10mg10mg£600.00
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TAR-T60128-25mg25mg£863.00
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TAR-T60128-50mg50mg£1,179.00
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TAR-T60128-100mg100mg£1,589.00
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TAR-T60128-500mg500mg£3,115.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

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Documents

Further Information

Bioactivity:
N,N-Didesethyl Sunitinib Hydrochloride is a potent AMPK inhibitor with IC50 of 393 nM and 141 nM for AMPKα1 and AMPK2,respectively.
CAS:
873077-70-4
Molecular Weight:
378.83
Pathway:
Chromatin/Epigenetic|PI3K/Akt/mTOR signaling
Purity:
0.971
SMILES:
NCCNC(C1=C(C)NC(/C=C(C2=C(N3)C=CC(F)=C2)\C3=O)=C1C)=O.Cl
Target:
AMPK

References

Matheson CJ, et al. Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors. Eur J Med Chem. 2020 Jul 1;197:112316.