USP8-IN-1

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TargetMol
Product Code: TAR-T60146
Supplier: TargetMol
CodeSizePrice
TAR-T60146-1mg1mg£140.00
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TAR-T60146-5mg5mg£242.00
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TAR-T60146-1mL1 mL * 10 mM (in DMSO)£259.00
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Quantity:
TAR-T60146-10mg10mg£322.00
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Quantity:
TAR-T60146-25mg25mg£499.00
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Quantity:
TAR-T60146-50mg50mg£687.00
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Quantity:
TAR-T60146-100mg100mg£938.00
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Quantity:
TAR-T60146-500mg500mg£1,805.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 uM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 uM [1].
CAS:
2477650-96-5
Molecular Weight:
387.46
Pathway:
Ubiquitination|Cell Cycle/Checkpoint|DNA Damage/DNA Repair
Purity:
0.9801
SMILES:
O=N(=O)C1=CC=C(C=C1)NC(=S)N2CCN(C3=CC=C(OC)C=C3N)CC2
Target:
DUB

References

Zhiyu Li, et al. USP8 inhibitor and preparation method and application thereof. CN111138358A.