STX-0119

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TargetMol
Product Code: TAR-T60160
Supplier: TargetMol
CodeSizePrice
TAR-T60160-1mg1mg£103.00
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TAR-T60160-5mg5mg£148.00
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TAR-T60160-1mL1 mL * 10 mM (in DMSO)£149.00
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Quantity:
TAR-T60160-10mg10mg£195.00
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Quantity:
TAR-T60160-25mg25mg£322.00
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Quantity:
TAR-T60160-50mg50mg£483.00
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Quantity:
TAR-T60160-100mg100mg£670.00
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Quantity:
TAR-T60160-500mg500mg£1,324.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 uM.
CAS:
851095-32-4
Molecular Weight:
382.37
Pathway:
JAK/STAT signaling|Stem Cells
Purity:
0.9942
SMILES:
O=C(NC1=NN=C(O1)C=2OC=CC2)C3=CC(=NC=4C=CC=CC43)C=5C=CC=CC5
Target:
STAT

References

Matsuno K, et al. Identification of a New Series of STAT3 Inhibitors by Virtual Screening. ACS Med Chem Lett. 2010 Jul 13;1(8):371-5.