YAP/TAZ inhibitor-2?

TargetMol
Product Code: TAR-T60218
Supplier: TargetMol
CodeSizePrice
TAR-T60218-1mg1mg£138.00
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TAR-T60218-2mg2mg£168.00
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TAR-T60218-5mg5mg£229.00
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TAR-T60218-1mL1 mL * 10 mM (in DMSO)£246.00
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TAR-T60218-10mg10mg£322.00
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TAR-T60218-25mg25mg£495.00
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TAR-T60218-50mg50mg£683.00
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TAR-T60218-100mg100mg£930.00
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TAR-T60218-500mg500mg£1,781.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC 50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative and antitumor activity [1].
CAS:
2762617-31-0
Molecular Weight:
390.33
Pathway:
Stem Cells
Purity:
0.9884
SMILES:
O=C(C(F)=C)N1CC(N2N=C(C=3C=CC(=CC3)C(F)(F)F)C=4C=CC=NC42)C1
Target:
YAP

References

Xu, xiaofeng, et al. Bicyclic compounds, compositions and use thereof. WO2022037568A1.