Atamestane
Code | Size | Price |
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TAR-T60664-1mg | 1mg | £160.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T60664-5mg | 5mg | £279.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T60664-10mg | 10mg | £384.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T60664-25mg | 25mg | £595.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T60664-50mg | 50mg | £816.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T60664-100mg | 100mg | £1,083.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T60664-500mg | 500mg | £2,103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Atamestane is a competitive, irreversible inhibitor of estrogen biosynthesis, a specific aromatase inhibitor that selectively blocks estrogen biosynthesis resulting from the aromatization of androstenedione and testosterone.Atamestane can be used in the study of benign prostatic hyperplasia (BPH).
CAS:
96301-34-7
Formula:
C20H26O2
Molecular Weight:
298.42
Pathway:
Endocrinology/Hormones
Purity:
0.9841
SMILES:
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)C(=O)CC4)[H])(CCC1=CC(=O)C=C2C)[H])[H]
Target:
Aromatase|Estrogen Receptor/ERR
References
Muller M, et al. Effects of dehydroepiandrosterone and atamestane supplementation on frailty in elderly men. J Clin Endocrinol Metab. 2006;91(10):3988-3991.
Sabnis GJ, et al. Toremifene-atamestane; alone or in combination: predictions from the preclinical intratumoral aromatase model. J Steroid Biochem Mol Biol. 2008;108(1-2):1-7.
Nishino Y, et al. Antitumor effect of a specific aromatase inhibitor, 1-methyl-androsta-1,4-diene-3,17-dione (atamestane), in female rats bearing DMBA-induced mammary tumors. J Steroid Biochem. 1989;34(1-6):435-437.
el Etreby MF. Atamestane: an aromatase inhibitor for the treatment of benign prostatic hyperplasia. A short review. J Steroid Biochem Mol Biol. 1993;44(4-6):565-572.