TAK-653

TargetMol
Product Code: TAR-T61518
Supplier: TargetMol
CodeSizePrice
TAR-T61518-1mg1mg£103.00
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TAR-T61518-5mg5mg£148.00
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Quantity:
TAR-T61518-10mg10mg£195.00
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Quantity:
TAR-T61518-25mg25mg£322.00
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Quantity:
TAR-T61518-50mg50mg£470.00
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Quantity:
TAR-T61518-100mg100mg£651.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
TAK-653, a selective positive allosteric modulator (PAM) of AMPA receptors exhibiting minimal agonistic activity, elicits an antidepressant-like response while maintaining a favorable safety profile in rat models.
CAS:
1358751-06-0
Molecular Weight:
373.47
Pathway:
Membrane transporter/Ion channel|Neuroscience
Purity:
0.9918
SMILES:
O=S1(=O)N=C2C(=NC(=CN2CC1)C)C3=CC=C(OC4CCCCC4)C=C3
Target:
iGluR

References

Hara H, et al. TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats. Pharmacol Biochem Behav. 2021 Dec;211:173289.