AMPK activator 4

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TargetMol
Product Code: TAR-T62238
Supplier: TargetMol
CodeSizePrice
TAR-T62238-1mg1mg£137.00
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TAR-T62238-5mg5mg£226.00
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TAR-T62238-1mL1 mL * 10 mM (in DMSO)£252.00
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TAR-T62238-10mg10mg£369.00
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TAR-T62238-25mg25mg£573.00
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TAR-T62238-50mg50mg£787.00
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Quantity:
TAR-T62238-100mg100mg£1,050.00
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TAR-T62238-500mg500mg£2,022.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

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Documents

Further Information

Bioactivity:
AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I. AMPK activator 4 selectively activates AMPK in muscle tissue and dose-dependently improves glucose tolerance in normal mice, significantly reduces fasting glucose levels and improves insulin resistance in db/db diabetic mice.AMPK activator 4 has hypoglycemic effects. activator 4 has hypoglycemic effects.
CAS:
2493239-46-4
Formula:
C24H21ClN2O3
Molecular Weight:
420.89
Pathway:
PI3K/Akt/mTOR signaling|Chromatin/Epigenetic
Purity:
0.9917
SMILES:
N#CC1=CC=C(C=C1)COC2=CC=C(C=C2)NC(=O)C(OC3=CC=C(Cl)C=C3)(C)C
Target:
AMPK

References

Sun G, et al. Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I. Eur J Med Chem. 2020;200:112466.