RIPK1-IN-9

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TargetMol
Product Code: TAR-T63055
Supplier: TargetMol
CodeSizePrice
TAR-T63055-1mg1mg£360.00
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TAR-T63055-5mg5mg£766.00
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Quantity:
TAR-T63055-1mL1 mL * 10 mM (in DMSO)£871.00
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Quantity:
TAR-T63055-10mg10mg£1,026.00
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Quantity:
TAR-T63055-25mg25mg£1,492.00
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Quantity:
TAR-T63055-50mg50mg£1,982.00
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Quantity:
TAR-T63055-100mg100mg£2,657.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
RIPK1-IN-9 is a potent and selective inhibitor of RIPK1, a dihydronaphthone compound, which inhibits U937 and L929 cells with an IC50 of 2 nM and 1.3 nM, respectively.
CAS:
2682889-57-0
Molecular Weight:
472.51
Pathway:
Apoptosis|NF-κb
Purity:
0.9875
SMILES:
O=C1C=2C=C(C=NC2CCN1CC3=CC(F)=CC=C3OC4CCCC4)C=5C=CN6N=C(N=C6C5)N
Target:
RIP kinase

References

Fusheng Zhou, et al. Dihydronaphthyridone compounds, their preparation and pharmaceutical uses. WO2021160109A1.