Ki16198

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TargetMol
Product Code: TAR-T6347
Supplier: TargetMol
CodeSizePrice
TAR-T6347-1mg1mg£98.00
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TAR-T6347-5mg5mg£135.00
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TAR-T6347-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T6347-10mg10mg£182.00
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TAR-T6347-25mg25mg£303.00
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TAR-T6347-50mg50mg£436.00
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Quantity:
TAR-T6347-100mg100mg£610.00
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TAR-T6347-500mg500mg£1,219.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 uM and 0.93 uM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.
CAS:
355025-13-7
Molecular Weight:
488.98
Pathway:
GPCR/G Protein
Purity:
0.976
SMILES:
O=C(OC(C=1C=CC=CC1Cl)C)NC2=C(ON=C2C)C=3C=CC(=CC3)CSCCC(=O)OC
Target:
LPL Receptor|LPA Receptor

References

Komachi M, et al. Cancer Sci, 2012, 103(6), 1099-1104. Shano S, et al. Biochim Biophys Acta, 2008, 1783(5), 748-759.