ML251

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TargetMol
Product Code: TAR-T64320
Supplier: TargetMol
CodeSizePrice
TAR-T64320-1mg1mg£179.00
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TAR-T64320-5mg5mg£303.00
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TAR-T64320-1mL1 mL * 10 mM (in DMSO)£325.00
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TAR-T64320-10mg10mg£436.00
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TAR-T64320-25mg25mg£675.00
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TAR-T64320-50mg50mg£922.00
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TAR-T64320-100mg100mg£1,219.00
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TAR-T64320-500mg500mg£2,368.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

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Documents

Further Information

Bioactivity:
ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 uM) and T. cruzi PFK (IC50=0.13 uM). ML251 can be used for the research of parasite[1].
CAS:
1486482-16-9
Molecular Weight:
426.27
Pathway:
Microbiology/Virology|Metabolism
Purity:
0.9979
SMILES:
O=C(Cc(cc1)cc(Cl)c1Cl)Nc(cc1)ccc1S(Nc1nocc1)(=O)=O
Target:
Glucokinase|Parasite

References

Brimacombe KR, et al. Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett. 2013;5(1):12-17.