TargetMol

Holomycin

Product Code:
 
TAR-T67731
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T67731-1mg1mg£470.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T67731-1mL1 mL * 10 mM (in DMSO)£870.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T67731-5mg5mg£978.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T67731-10mg10mg£1,291.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T67731-25mg25mg£1,878.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T67731-50mg50mg£2,456.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T67731-100mg100mg£3,259.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Holomycin is a secondary metabolite of dithiopyrrolidone. HolomycinHolomycin, an antibiotic secondary metabolite, is required for the biofilm formation of natural photogenic Bacillus galatheae S2753 and is also a broad-spectrum antibiotic. holomycin promotes biofilm formation of S2753 through its alene-disthionyl group. Holomycin has antitumor activity and is involved in RNA synthesis.
CAS:
488-04-0
Molecular Weight:
214.27
Pathway:
Cell Cycle/Checkpoint|DNA Damage/DNA Repair
Purity:
0.9809
SMILES:
O=C1NC2=CSSC2=C1NC(=O)C
Target:
DNA/RNA Synthesis

References

Oliva B, et al. Antimicrobial properties and mode of action of the pyrrothine holomycin. Antimicrob Agents Chemother. 2001;45(2):532-539. Yin H, et al. Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1. Appl Environ Microbiol. 2012;78(9):3431-3441. Liras P. Holomycin, a dithiolopyrrolone compound produced by Streptomyces clavuligerus. Appl Microbiol Biotechnol. 2014;98(3):1023-1030.