AM5992

TargetMol
Product Code: TAR-T67780
Supplier: TargetMol
CodeSizePrice
TAR-T67780-1mg1mg£227.00
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Quantity:
TAR-T67780-5mg5mg£431.00
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Quantity:
TAR-T67780-10mg10mg£613.00
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Quantity:
TAR-T67780-25mg25mg£997.00
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Quantity:
TAR-T67780-50mg50mg£1,458.00
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Quantity:
TAR-T67780-100mg100mg£2,155.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
AM5992 (example 195) is a potent CDK4 and CDK6 inhibitor (CDK4, IC50= 0.013 uM). AM5992 can be used for the research of CDK4-mediated disorders.
CAS:
1169694-98-7
Molecular Weight:
504.6
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
FC1=NC=CC=2C=3C=NC(=NC3N(C12)C4CCCC4)NC5=NC=C(C=C5)N6CCC(N(C)CCO)CC6
Target:
CDK

References

Richard V. Connors, et al. Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors. WO2009085185A1.