HPPE

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TargetMol
Product Code: TAR-T67920
Supplier: TargetMol
CodeSizePrice
TAR-T67920-1mg1mg£109.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T67920-5mg5mg£161.00
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TAR-T67920-1mL1 mL * 10 mM (in DMSO)£180.00
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Quantity:
TAR-T67920-10mg10mg£213.00
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Quantity:
TAR-T67920-25mg25mg£309.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T67920-50mg50mg£434.00
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Quantity:
TAR-T67920-100mg100mg£597.00
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Quantity:
TAR-T67920-500mg500mg£1,163.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
HPPE is a selective inhibitor of Bach1 that acts non-electrophilically. HPPE targets the heme-binding sites on the Bach1 protein and leads to the alleviation of Bach1-mediated repression.
CAS:
1325721-55-8
Molecular Weight:
479.48
Purity:
0.9822
SMILES:
O=C(NCCOCCO)C=1C=CC2=C(N=C(NC3=NC=4C=CC(=CC4S3)C(F)(F)F)N2C)C1

References

Ahuja M, et al. Bach1 derepression is neuroprotective in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A. 2021 Nov 9;118(45):e2111643118. Attucks, et al. Methods of inhibiting osteoclastogenesis and osteoclast activity using fused imidazole derivatives. WO2020117886 A1