Sulotroban
Code | Size | Price |
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TAR-T68022-1mg | 1mg | £143.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68022-5mg | 5mg | £239.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68022-10mg | 10mg | £319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68022-25mg | 25mg | £541.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68022-50mg | 50mg | £705.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
CAS:
72131-33-0
Molecular Weight:
335.38
Pathway:
Metabolism|DNA Damage/DNA Repair
Purity:
0.9879
SMILES:
O=C(O)COC1=CC=C(C=C1)CCNS(=O)(=O)C=2C=CC=CC2
Target:
PPAR
References
Nossaman BD, et al. Blockade of thromboxane/endoperoxide receptor-mediated responses in the pulmonary vascular bed of the cat by sulotroban. Eur J Pharmacol. 1992;213(1):1-7.
St?rzebecher S, et al. The PGI2-analogue iloprost and the TXA2-receptor antagonist sulotroban synergistically inhibit TXA2-dependent platelet activation. Prostaglandins. 1988;36(6):751-760.
Fujita T, et al. Effect of selective endoperoxide/thromboxane A2 receptor antagonism with sulotroban on tPA-induced thrombolysis in a rabbit model of femoral arterial thrombosis. Fundam Clin Pharmacol. 1989;3(6):643-653.
Mann WA, et al. Characterization of the renal effects and renal elimination of sulotroban in the dog. J Pharmacol Exp Ther. 1991;259(3):1231-1240.
Finci L, et al. Sulotroban during and after coronary angioplasty. A double-blind, placebo controlled study. Z Kardiol. 1989;78 Suppl 3:50-54.