Losulazine
Code | Size | Price |
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TAR-T68095-1mg | 1mg | £139.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T68095-5mg | 5mg | £239.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T68095-10mg | 10mg | £319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T68095-25mg | 25mg | £541.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68095-50mg | 50mg | £697.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68095-100mg | 100mg | £946.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68095-500mg | 500mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Losulazine is a peripheral sympathetic antihypertensive compound that can be taken orally. Losulazine causes relatively modest, transient depletion of dopamine and norepinephrine in brain regions protected by the blood-brain barrier.
CAS:
72141-57-2
Molecular Weight:
558.55
Pathway:
GPCR/G Protein|Neuroscience
Purity:
0.998
SMILES:
O=C(C1=CC=C(C=C1)NC=2C=CN=C3C=C(C=CC32)C(F)(F)F)N4CCN(CC4)S(=O)(=O)C5=CC=C(F)C=C5
Target:
Dopamine Receptor|Norepinephrine
References
Mesfin GM, et al. Mechanism of anestrus in rats treated with an antihypertensive agent, losulazine hydrochloride. Toxicol Appl Pharmacol. 1987 Jan;87(1):91-101.
Pals DT, et al. Cardiovascular effects of losulazine hydrochloride, a peripheral norepinephrine-depleting agent, in nonhuman primates. J Pharmacol Exp Ther. 1985 Feb;232(2):407-12.