Scio-323

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TargetMol
Product Code: TAR-T68139
Supplier: TargetMol
CodeSizePrice
TAR-T68139-1mg1mg£227.00
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TAR-T68139-5mg5mg£416.00
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TAR-T68139-1mL1 mL * 10 mM (in DMSO)£486.00
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TAR-T68139-10mg10mg£581.00
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TAR-T68139-25mg25mg£863.00
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TAR-T68139-50mg50mg£1,163.00
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TAR-T68139-100mg100mg£1,540.00
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TAR-T68139-500mg500mg£3,026.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
Scio-323 is an orally available p38 mitogen-activated protein (MAPK) kinase inhibitor.
CAS:
309913-51-7
Formula:
C27H30FN3O4
Molecular Weight:
479.54
Pathway:
MAPK
Purity:
0.98
SMILES:
O=C(C(=O)N(C)C)C1=CN(C=2C=C(OC)C(=CC12)C(=O)N3CCC(CC4=CC=C(F)C=C4)CC3)C
Target:
p38 MAPK

References

Ma T, et al. Efficacy of a p38 mitogen activated protein kinase inhibitor in mitigating an established inflammatory reaction to polyethylene particles in vivo. J Biomed Mater Res A. 2009;89(1):117-123. Higgins, et al. Treatment of osteolytic lesions associated with multiple myeloma by inhibition of p38 map kinase. US20060058296A1. Kirschenbaum, et al. Methods of screening for compounds that selectively inhibit p38 MAP kinase ? isoenzymes for use as immunomodulators. US20050043212A1