TC-2216
Code | Size | Price |
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TAR-T68154-1mg | 1mg | £140.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68154-5mg | 5mg | £231.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68154-10mg | 10mg | £311.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68154-25mg | 25mg | £541.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68154-50mg | 50mg | £713.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68154-100mg | 100mg | £946.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T68154-500mg | 500mg | £1,862.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.
CAS:
646055-67-6
Molecular Weight:
203.28
Pathway:
Neuroscience
Purity:
0.98
SMILES:
N=1C=CC=C(C1)N2CCC3(NCCC3)C2
Target:
AChR
References
Lippiello PM, et al. TC-5214 (S-(+)-mecamylamine): a neuronal nicotinic receptor modulator with antidepressant activity. CNS Neurosci Ther. 2008;14(4):266-277.
Lee R F, et al. Citrus blight: attempts to get remission of symptoms by chemotherapy. Proceedings of the Florida State Horticultural Society. 1981; 94: 21-24.
Strachan JP, et al. Diazaspirocyclic compounds as selective ligands for the ?4?2 nicotinic acetylcholine receptor. Bioorg Med Chem Lett. 2012;22(15):5089-5092.
Sippy KB, et al. Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors. Bioorg Med Chem Lett. 2009;19(6):1682-168
Capelli AM, et al. Stable expression and functional characterization of a human nicotinic acetylcholine receptor with ?6?2 properties: discovery of selective antagonists. Br J Pharmacol. 2011;163(2):313-329.