RIG012

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TargetMol
Product Code: TAR-T73486
Supplier: TargetMol
CodeSizePrice
TAR-T73486-1mg1mg£206.00
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TAR-T73486-5mg5mg£410.00
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Quantity:
TAR-T73486-10mg10mg£574.00
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Quantity:
TAR-T73486-25mg25mg£858.00
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Quantity:
TAR-T73486-50mg50mg£1,139.00
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Quantity:
TAR-T73486-100mg100mg£1,508.00
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Quantity:
TAR-T73486-500mg500mg£2,986.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
RIG012 is a potent RIG-I inhibitor with an IC50 value of 0.71 uM measured by NADH-coupled ATPase.RIG012 inhibited the expression of IFN-β and ISG hRsad2.
CAS:
2642218-43-5
Molecular Weight:
359.42
Purity:
0.98
SMILES:
O=C1N=C2C=3C=CC=CC3C(=O)C(OCC=4C=CC=CC4)=C2C1(CC)CC

References

David C Rawling, et al. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15(2):311-317.