Bococizumab

TargetMol
Product Code: TAR-T76739
Product Group: Primary Antibodies
Supplier: TargetMol
CodeSizePrice
TAR-T76739-1mg1mg£349.00
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TAR-T76739-5mg5mg£771.00
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TAR-T76739-10mg10mg£1,187.00
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Quantity:
TAR-T76739-25mg25mg£1,661.00
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Quantity:
TAR-T76739-50mg50mg£2,311.00
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Quantity:
TAR-T76739-100mg100mg£3,099.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Bococizumab(PF-04950615) is a humanized mAb against PCSK9 and an inhibitor of the synthesis of PCSK9 in the liver that reduces the amount of low-density lipoprotein cholesterol (LDL-C) in the blood.Bococizumab is used to treat hypercholesterolemia.
CAS:
1407495-02-6
Purity:
0.98

References

Koutaro Yokote, et al. Efficacy and Safety of Bococizumab (RN316/PF-04950615), a Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, in Hypercholesterolemic Japanese Subjects Receiving a Stable Dose of Atorvastatin or Treatment-Naive - Results From a Randomized, Placebo-Controlled, Dose-Ranging Study. Circ J. 2017 Sep 25;81(10):1496-1505. Sarah N Campion, et al. Decreased maternal and fetal cholesterol following maternal bococizumab (anti-PCSK9 monoclonal antibody) administration does not affect rat embryo-fetal development. Regul Toxicol Pharmacol. 2015 Nov;73(2):562-70.