TargetMol

MyD88-IN-1

Product Code:
 
TAR-T77353
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T77353-1mg1mg£125.00
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TAR-T77353-5mg5mg£197.00
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TAR-T77353-1mL1 mL * 10 mM (in DMSO)£209.00
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TAR-T77353-10mg10mg£261.00
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TAR-T77353-25mg25mg£386.00
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TAR-T77353-50mg50mg£548.00
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Quantity:
TAR-T77353-100mg100mg£752.00
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Quantity:
TAR-T77353-500mg500mg£1,460.00
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This product comes from: United States.
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Further Information

Bioactivity:
MyD88-IN-1 is a potent MyD88 inhibitor MyD88-IN-1 has anti-inflammatory activity and inhibits downstream inflammatory signaling pathways, including the NF-κB pathway, of members of the Toll-like receptor (TLR) and interleukin-1 (IL-1) receptor family MyD88-IN-1 may be used for the study of cancer and the treatment of inflammation.
CAS:
2911609-80-6
Molecular Weight:
528.54
Pathway:
NF-κb|Immunology/Inflammation
Purity:
0.98
SMILES:
O=N(=O)C1=CC=CC(=C1)CN2CCN(C3=CC=C(C=C3N(=O)=O)S(=O)(=O)NC4=CN=C(OC)C=C4)CC2
Target:
TLR|NF-κB|MyD88|IL Receptor

References

Chen P, et al. Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen. J Med Chem. 2023;66(10):6938-6958.