VU533

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TargetMol
Product Code: TAR-T77616
Supplier: TargetMol
CodeSizePrice
TAR-T77616-1mg1mg£227.00
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TAR-T77616-5mg5mg£416.00
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Quantity:
TAR-T77616-10mg10mg£581.00
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Quantity:
TAR-T77616-25mg25mg£863.00
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Quantity:
TAR-T77616-50mg50mg£1,163.00
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Quantity:
TAR-T77616-100mg100mg£1,540.00
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Quantity:
TAR-T77616-500mg500mg£3,026.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
VU533 is a NAPE-PLD activator with an EC50 value of 0.30 uM.VU533 enhances NAPE-PLD activity and increases macrophage cytosolic burial.VU533 may be used in diseases associated with cardiometabolism.
CAS:
923417-09-8
Molecular Weight:
447.55
Pathway:
Metabolism
Purity:
0.98
SMILES:
O=C(NC1=NC=2C(S1)=C(C=CC2C)C)C3CCN(CC3)S(=O)(=O)C4=CC=C(F)C=C4
Target:
Phospholipase

References

Zarrow JE, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. bioRxiv [Preprint]. 2023 Feb 28:2023.01.25.525554.