Z16078526

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TargetMol
Product Code: TAR-T77621
Supplier: TargetMol
CodeSizePrice
TAR-T77621-1mg1mg£109.00
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TAR-T77621-5mg5mg£165.00
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TAR-T77621-10mg10mg£227.00
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TAR-T77621-25mg25mg£404.00
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TAR-T77621-50mg50mg£566.00
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TAR-T77621-100mg100mg£775.00
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TAR-T77621-500mg500mg£1,508.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
Z16078526 induces endogenous Ucp1 expression, promotes?p38 MAPK?phosphorylation and lipolysis in primary mouse brown adipocytes. Z16078526 activates thermogenic gene expression and mitochondrial activity (uncoupled respiration) in mouse brown adipocytes. Z16078526 also stimulates thermogenesis in the mouse
CAS:
852222-94-7
Formula:
C18H17N3O4S
Molecular Weight:
371.41
Pathway:
Metabolism|MAPK
Purity:
0.98
SMILES:
O=C1N=C(SCC(=O)NC2=CC=C(OC)C=C2OC)NC=3C=CC=CC13
Target:
p38 MAPK|Mitochondrial Metabolism

References

Vergnes L, et al. Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. J Biol Chem. 2020 Oct 30;295(44):15054-15069.