Aβ42-IN-2

TargetMol
Product Code: TAR-T9641
Supplier: TargetMol
CodeSizePrice
TAR-T9641-1mg1mg£164.00
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TAR-T9641-5mg5mg£303.00
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TAR-T9641-1mL1 mL * 10 mM (in DMSO)£326.00
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Quantity:
TAR-T9641-10mg10mg£438.00
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Quantity:
TAR-T9641-25mg25mg£704.00
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TAR-T9641-50mg50mg£938.00
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Quantity:
TAR-T9641-100mg100mg£1,267.00
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TAR-T9641-500mg500mg£2,464.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

1 / 1

Further Information

Bioactivity:
Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].
CAS:
1914989-80-2
Molecular Weight:
430.5
Pathway:
Neuroscience|Proteases/Proteasome|Stem Cells
Purity:
1
SMILES:
O(C)C1=C(C=CC(=N1)C2=CC(C)=C(N[C@@H](C)C3=CC=C(OC)C=C3)N=N2)N4C=NC(C)=C4
Target:
Gamma-secretase

References

Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1.