TargetMol

Stafib-2

Product Code:
 
TAR-T9646
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T9646-1mg1mg£285.00
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TAR-T9646-5mg5mg£602.00
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TAR-T9646-10mg10mg£827.00
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TAR-T9646-1mL1 mL * 10 mM (in DMSO)£846.00
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TAR-T9646-25mg25mg£1,187.00
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TAR-T9646-50mg50mg£1,581.00
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Quantity:
TAR-T9646-100mg100mg£2,127.00
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This product comes from: United States.
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Further Information

Bioactivity:
Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 uM, respectively.Stafib-2 has poor cell permeability.
CAS:
2097938-74-2
Molecular Weight:
644.46
Pathway:
Stem Cells|JAK/STAT signaling
Purity:
0.9897
SMILES:
O=C(NC1=CC=C(OC=2C=CC=CC2)C=C1)C3=CC=C(OCC(=O)NCC4=CC=C(OP(=O)(O)O)C(OP(=O)(O)O)=C4)C=C3
Target:
STAT

References

Elumalai N, et al. Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b. Sci Rep. 2017;7(1):819. Elumalai N, et al. Halogen-substituted catechol bisphosphates are potent and selective inhibitors of the transcription factor STAT5b. Bioorg Med Chem. 2017;25(14):3871-3882.