TargetMol

4-methoxylonchocarpin

Product Code:
 
TAR-TN7235
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TN7235-1mg1mg£227.00
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TAR-TN7235-5mg5mg£464.00
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TAR-TN7235-10mg10mg£645.00
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TAR-TN7235-25mg25mg£946.00
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TAR-TN7235-50mg50mg£1,259.00
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Further Information

Bioactivity:
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in macrophages and suppressed TNBS-induced colitis in mice.
CAS:
51589-67-4
Formula:
C21H20O4
Molecular Weight:
336.38
Pathway:
Apoptosis|NF-κb
Purity:
0.98
SMILES:
OC1=C2C(OC(C)(C)C=C2)=CC=C1C(/C=C/C3=CC=C(OC)C=C3)=O
Target:
NF-κB|TNF

References

Hussain H, et al. 4-Benzyloxylonchocarpin and Muracatanes A-C from Ranunculus muricatus L. and Their Biological Effects. Biomolecules. 2020;10(11):1562. Jang HM, et al. 4-Methoxylonchocarpin attenuates inflammation by inhibiting lipopolysaccharide binding to Toll-like receptor of macrophages and M1 macrophage polarization. Int Immunopharmacol. 2017;45:90-97. Li J, Kang Z, et al. Potent insecticidal activity of Eleocharis dulcis (Burm. f.) Trin peel extract and its main components against aphids. Pest Manag Sci. 2023;79(4):1295-1304. Ngadjui BT, et al. Prenylated flavonoids from the aerial parts of Dorstenia mannii. Phytochemistry. 2000;55(8):915-919.