Cephalandole B
Code | Size | Price |
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TAR-TN7236-1mg | 1mg | £227.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7236-5mg | 5mg | £464.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7236-10mg | 10mg | £645.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7236-25mg | 25mg | £946.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7236-50mg | 50mg | £1,259.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
cephalandole B, an indole alkaloid isolated from cyanide, significantly inhibited IL-17A gene expression and suppressed IL-17A luciferase reporter in Jukat cells in a dose-dependent manner.
CAS:
915315-44-5
Formula:
C17H14N2O3
Molecular Weight:
294.3
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
O=C(OC)C=1C=CC=CC1NC(=O)C2=CNC=3C=CC=CC32
Target:
IL Receptor
References
Mason JJ, et al. Synthetic studies of cephalandole alkaloids and the revised structure of cephalandole A. J Nat Prod. 2008;71(8):1447-1450.
Lee CL, et al. IL-17A inhibitions of indole alkaloids from traditional Chinese medicine Qing Dai. J Ethnopharmacol. 2020;255:112772.