TargetMol

Sulfosuccinimidyl oleate

Product Code:
 
TAR-T13036
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T13036-5mg5mg£850.00
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Quantity:
TAR-T13036-50mg50mg£1,661.00
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Quantity:
TAR-T13036-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate binds the CD36 receptor on the surface of microglia. Sulfosuccinimidyl oleate is neuroprotective and alleviates stroke-induced neuroinflammation [1] [2].
CAS:
135661-44-8
Formula:
C22H37NO7S
Molecular Weight:
459.6
Pathway:
Autophagy
Purity:
0.98
SMILES:
O(C(CCCCCCC/C=C\CCCCCCCC)=O)N1C(=O)C(S(=O)(=O)O)CC1=O
Target:
Mitophagy

References

Dhungana H, et al. Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation. J Neuroinflammation. 2017 Dec 4;14(1):237. Drahota Z, et al. Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain. Biochem Biophys Res Commun. 2010 Jan 15;391(3):1348-51.