TargetMol

Resolvin D1

Product Code:
 
TAR-T13864
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Resolvin D1 is an endogenous pro-resolving mediator of inflammation, blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α?mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages.
CAS:
872993-05-0
Formula:
C22H32O5
Molecular Weight:
376.49
Purity:
0.98
SMILES:
[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@H](C/C=C\CC)O)O)(C/C=C\CCC(O)=O)O

References

Benabdoun HA, et al. In vitro and in vivo assessment of the proresolutive and antiresorptive actions of resolvin D1: relevance to arthritis. Arthritis Res Ther. 2019 Mar 12;21(1):72. Schmid M, et al. Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32. J Immunol. 2016 Apr 15;196(8):3429-37. Gao Y, et al. Resolvin D1 Improves the Resolution of Inflammation via Activating NF-?B p50/p50-Mediated Cyclooxygenase-2 Expression in Acute Respiratory Distress Syndrome. J Immunol. 2017 Aug 9. pii: ji1700315.