AP-4

TargetMol
Product Code: TAR-T19863
Supplier: TargetMol
CodeSizePrice
TAR-T19863-5mg5mg£850.00
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Quantity:
TAR-T19863-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T19863-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
AP-4 is an antagonist of the NMDA glutamate receptor.
CAS:
20263-07-4
Formula:
C4H10NO5P
Molecular Weight:
183.1
Purity:
0.98
SMILES:
O=P(O)(O)CCC(N)C(O)=O

References

Ebrahimi-Fakhari D, Cheng C, Dies K, Diplock A, Pier DB, Ryan CS, Lanpher BC, Hirst J, Chung WK, Sahin M, Rosser E, Darras B, Bennett JT; CureSPG47. Clinical and genetic characterization of AP4B1-associated SPG47. Am J Med Genet A. 2018 Feb;176(2):311-318. doi: 10.1002/ajmg.a.38561. Epub 2017 Nov 28. PubMed PMID: 29193663. Rogge DE, Nicklas JY, Haas SA, Reuter DA, Saugel B. Continuous Noninvasive Arterial Pressure Monitoring Using the Vascular Unloading Technique (CNAP System) in Obese Patients During Laparoscopic Bariatric Operations. Anesth Analg. 2018 Feb;126(2):454-463. doi: 10.1213/ANE.0000000000002660. PubMed PMID: 29261549. Mattera R, Park SY, De Pace R, Guardia CM, Bonifacino JS. AP-4 mediates export of ATG9A from the trans-Golgi network to promote autophagosome formation. Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10697-E10706. doi: 10.1073/pnas.1717327114. Epub 2017 Nov 27. PubMed PMID: 29180427; PubMed Central PMCID: PMC5740629. Hatsugai N, Nakatsuji A, Unten O, Ogasawara K, Kondo M, Nishimura M, Shimada T, Katagiri F, Hara-Nishimura I. Involvement of Adapter Protein Complex 4 in Hypersensitive Cell Death Induced by Avirulent Bacteria. Plant Physiol. 2017 Dec 14. pii: pp.01610.2017. doi: 10.1104/pp.17.01610. [Epub ahead of print] PubMed PMID: 29242374.