LT175
Code | Size | Price |
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TAR-T21812-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T21812-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T21812-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
LT175 is a dual PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties. LT175 is an orally active partial agonist against PPARγ(hPPARα: EC 50 =0.22 um; mPPARα: EC 50 =0.26 um; hPPARγ: EC 50 =0.48 um). LT175 interacts with PPARγ and affects the recruitment of the coregulators cyclic-AMP response element-binding protein-binding protein and nuclear corepressor 1 (NCoR1). LT175 interacts with PPARγ in a hydrophobic region called ?diphenyl pocket? [1].
CAS:
862901-87-9
Molecular Weight:
318.37
Purity:
0.98
SMILES:
O([C@@H](CC1=CC=CC=C1)C(O)=O)C2=CC=C(C=C2)C3=CC=CC=C3