TargetMol

γ-Acetylenic GABA hydrochloride

Product Code:
 
TAR-T40659L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T40659L-5mg5mg£111.00
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TAR-T40659L-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T40659L-10mg10mg£131.00
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TAR-T40659L-25mg25mg£173.00
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Quantity:
TAR-T40659L-50mg50mg£225.00
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This product comes from: United States.
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Further Information

Bioactivity:
γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.
CAS:
103451-26-9
Formula:
C6H10ClNO2
Molecular Weight:
163.6
Pathway:
Membrane transporter/Ion channel|Neuroscience|Metabolism
Purity:
0.9964
SMILES:
Cl.O=C(O)CCC(C#C)N
Target:
GABA Receptor|Transaminase

References

Palfreyman MG, et, al. The effect of gamma-acetylenic GABA, an enzyme-activated irreversible inhibitor of GABA-transaminase, on dopamine pathways of the extrapyramidal and limbic systems. Eur J Pharmacol. 1978 Aug 15;50(4):325-36. Casey DE, et, al. gamma-Acetylenic GABA in tardive dyskinesia. Arch Gen Psychiatry. 1980 Dec;37(12):1376-9. Alabed S, et, al. Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia. Cochrane Database Syst Rev. 2011 Apr 13;(4):CD000203.