EMI1

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TargetMol
Product Code: TAR-T61016
Supplier: TargetMol
CodeSizePrice
TAR-T61016-5mg5mg£115.00
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TAR-T61016-10mg10mg£148.00
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Quantity:
TAR-T61016-25mg25mg£230.00
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Quantity:
TAR-T61016-50mg50mg£334.00
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Quantity:
TAR-T61016-100mg100mg£495.00
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Quantity:
TAR-T61016-500mg500mg£978.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Documents

Further Information

Bioactivity:
EMI1 can be used in the mutant EGFR-associated, drug-resistant non-small-cell lung cancer(NSCLC) research. EMI1 is an inhibitor of EGFR L858R/T790M/C797S and EGFR ex19del/T790M/C797S [1].
CAS:
35773-42-3
Molecular Weight:
334.37
Pathway:
JAK/STAT signaling|Tyrosine Kinase/Adaptors|Angiogenesis
Purity:
1
SMILES:
O=C1OC2=CC(=CC=C2C=C1C3=NC=4C=CC=CC4O3)N(CC)CC
Target:
EGFR

References

Punit Saraon, et al. A drug discovery platform to identify compounds that inhibit EGFR triple mutants. Nat Chem Biol. 2020 May;16(5):577-586.