Mt KARI-IN-4
Code | Size | Price |
---|
TAR-T61395-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T61395-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T61395-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Mt KARI-IN-4 (compound 5c) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), demonstrating a Ki value of 5.48 uM. Additionally, Mt KARI-IN-4 displays inhibitory properties against Mtb H37Rv, with a minimum inhibitory concentration (MIC) of 0.78 uM. Importantly, this compound exhibits low levels of cytotoxicity, as evident from its half-maximal inhibitory concentration (IC 50 ) value of over 72 ug/mL against human embryonic kidney cells (HEK) [1].
CAS:
2413974-53-3
Molecular Weight:
365.36
Purity:
0.98
SMILES:
[O-][N+](=O)c1ccc(o1)-c1nnc(NC(=S)Nc2ccc(F)cc2)s1